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Currently you are able to watch "Breakthrough" streaming on Freevee for free with ads or buy it as download on Amazon Video, Apple TV. It is also possible to rent "Breakthrough" on Amazon Video, Apple TV online
Breakthrough tells the story of a renegade scientist’s quest to find a cure for cancer, the disease that killed his mother. Texan Jim Allison is a 2018 Nobel Prize winner for discovering how to prompt a cancer patient’s own immune system into defeating their disease, but for decades he waged an often-lonely struggle against the painful skepticism of the medical establishment.