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Robert Downey Jr.Dr. John DolittleAntonio BanderasKing RassouliMichael SheenDr. Blair MüdflyJim BroadbentLord Thomas BadgleyJessie BuckleyQueen VictoriaHarry CollettTommy StubbinsEmma ThompsonPoly (voice)Rami MalekChee-Chee (voice)John CenaYoshi (voice)Kumail NanjianiPlimpton (voice)Octavia SpencerDab-Dab (voice)Tom HollandJip (voice)Craig RobinsonKevin (voice)Ralph FiennesBarry (voice)Selena GomezBetsy (voice)Marion CotillardTutu (voice)Will ArnettJack Rabbit (voice) (uncredited)Kasia SmutniakLily DolittleCarmel LaniadoLady RoseFrances de la TourDragon (voice)Jason MantzoukasJames the Dragonfly (voice)Ralph InesonArnall StubbinsJoanna PageBethan StubbinsSonny Ashbourne SerkisArnall Stubbins Jr.Oliver ChrisSir GarethClive FrancisArchbishopPaul HolowatyNavy ManElliot Barnes-WorrellCaptain William DerrickMark UmbersLieutenantDavid SheinkopfDon CarpenterinoSid SagarJeff the PrisonerMartin PembertonPostmanTim TreloarHumphrey the Whale (voice)Jim CarrettaBeard Mouse and Leona (voice)Nick FisherMini the Sugar Glider (voice)Matt KingClydeRanjani BrowMouse (voice)Kelly StablesMouse (voice)Scott MenvilleArmy Ant (voice)Gia DavisBaby Animal (voice)Henry HolcombBaby Animal (voice)Kyrie McalpinBaby Animal (voice)Isley ZamoraBaby Animal (voice)Stewart ScudamorePirateSamson KayoPirateJohn-Luke RobertsPirate / Animal PerformerJoseph BalderramaPrisonerDaniel Hoffmann-GillPrisonerJane LeaneyAnimal PerformerJosh JefferiesOn Set Chee-Chee / Animal PerformerShaun McKeeOn Set Yoshi / Animal PerformerRichard SoamesAnimal Performer
After losing his wife seven years earlier, the eccentric Dr. John Dolittle, famed doctor and veterinarian of Queen Victoria’s England, hermits himself away behind the high walls of Dolittle Manor with only his menagerie of exotic animals for company. But when the young queen falls gravely ill, a reluctant Dolittle is forced to set sail on an epic adventure to a mythical island in search of a cure, regaining his wit and courage as he crosses old adversaries and discovers wondrous creatures.
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